RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
circ-ITCH
RNA ID
RNA Type
circRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
RT-qRT-PCR;western blot;luciferase reporter assay etc.
Target
NA
Pathway
NA
PubMed ID
34216220
Title
CircRNA circ-ITCH improves renal inflammation and fibrosis in streptozotocin-induced diabetic mice by regulating the miR-33a-5p/SIRT6 axis
Year
2021
Function
Circ-ITCH alleviated renal inflammation and fibrosis in STZ-induced diabetic mice by regulating the miR-33a-5p/SIRT6 axis.